Following are five big themes likely to dominate thinking of investors and traders in the coming week and the Reuters stories related to them.

1/A (BREXIT) RECKONING

Prime Minister Theresa May's long-awaited Brexit deal triggered a wave of ministerial resignations that has rocked her government and financial markets and raised chances of a snap election.

The pound took the hardest beating. Traders who had hung back from big sterling bets for much of 2018 rushed to sell it, fuelling its biggest daily drop against the euro since 2016. Gilt yields tumbled too and the FTSE index, which usually rises when sterling falls, lost that inverse correlation and closed flat after Thursday's mayhem.

One-month implied volatility on sterling -- basically a gauge of how much traders expect it to swing in a given period -- has climbed to over 15 percent. Not only is that double the volatility of the euro and almost triple yen and Swiss franc levels, it has now entered territory reserved for emerging currencies such as the Brazilian real and Turkish lira.

May might now need to survive a no-confidence vote, possibly on Tuesday. Even if she does, she has her work cut out to get the unpopular deal through parliament next month.