In Dubai, the index slipped 1.6 percent, with Emaar Properties EMAR.DU dropping 3.1 percent and Union Properties slumping 6.4 percent to hit their lowest levels since January 2016.
Dubai property prices sank 7.4 percent from a year earlier in the third quarter of 2018, accelerating from a 5.8 percent decline in the second quarter, the United Arab Emirates central bank said in a report on Tuesday.
DAMAC Properties also slid 4.3 percent to its lowest since March 2015.
The Abu Dhabi index lost 1.4 percent after registering its biggest gain in two years on Tuesday. The emirate's largest bank, First Abu Dhabi Bank , declined 2.3 percent after surging in the last session, its first trading day after its weighting in MSCI's emerging markets index doubled.
Aldar Properties dropped 2.5 percent, while Eshraq Properties ESHR.AD lost 3.1 percent.
Abu Dhabi residential real estate prices dropped 6.1 percent year-on-year in the third quarter after a 6.9 percent slide in the second quarter, the central bank report added.
Saudi Arabia's main index slipped 0.3 percent, with National Commercial Bank 1180.SE losing 0.6 percent and Al Rajhi Bankalso declining 0.6 percent.
The Egyptian blue-chip index lost 0.3 percent after slumping to an 18-month low on Tuesday. Eastern Co was down 2.2 percent and Heliopolis Co For Housing And Development lost 2.1 percent.
Qatar's index was flat with Qatar National Bank shedding 2.5 percent at 194 riyals after SICO downgraded the stock to 'sell' from 'buy', at a target price of 180 riyals.
SAUDI ARABIA * The index lost 0.3 percent to 7,884 points.
DUBAI * The index slid 1.6 percent to 2,632 points
ABU DHABI * The index fell 1.4 percent to 4,830 points
QATAR * The index was flat at 10,590 points.
KUWAIT * The index was up 0.4 percent at 5,390 points.
EGYPT * The index fell 0.3 percent to 12,587 points.
BAHRAIN * The index edged down 0.3 percent to 1,322 points.
OMAN * The index was up 0.4 percent at 4,552 points.
(Reporting by Abinaya Vijayaraghavan and Ateeq Shariff in Bengaluru; additional reporting by Saeed Azhar in Dubai; editing by Larry King) ((email@example.com; within U.S.+1 646 223 8780; outside U.S. +91 80 6749 2733; Reuters Messaging: firstname.lastname@example.org))