ABU DHABI- Abu Dhabi Health Services Company, (SEHA), the UAE’s largest healthcare network, successfully treated 17-month-old Emirati baby, Afra, who was diagnosed with spinal muscular atrophy (SMA).

SMA is a group of inherited diseases that damage nerve cells in the spinal cord called motor neurons. This damage is progressive (increases over time), affecting actions like swallowing, breathing, sitting, and walking.

SMA is passed on to children by parents through abnormal genes, with the most common form of SMA caused by an unusual or missing survival motor neuron 1 gene (SMN1 gene).

A specialised team at the Sheikh Khalifa Medical City (SKMC), part of the SEHA network, successfully diagnosed Afra with the rare genetic disease and developed a comprehensive treatment plan to prevent the condition from further deteriorating, including the provision of a particular type of genetic treatment that was imported from abroad specifically for Afra.

Dr. Mariam Buti Al Mazrouei, Chief Executive Director, SKMC, said: "SEHA is relentlessly devoted to providing world-class healthcare to members of our community through distinguished medical, technical and administrative staff using the latest in technology and pharmaceuticals available globally. Thanks to the UAE’s robust and ever-expanding healthcare landscape enabled by the visionary direction from authorities and leadership, we have fast, simple and streamlined access to integral tools and resources from abroad.

Afra’s journey towards recovery is a significant achievement, not just for the SEHA network but for the wider healthcare ecosystem in the country, as we provide hope and create impact for families with children diagnosed with SMA." Dr. Omar Ismail, Head of Pediatric Neurology and Pediatric Neurology Consultant, SKMC, said: "The key to successfully overcoming SMA is early diagnosis and implementation of a vigorous treatment strategy, this is to keep the nerves cells (neurons) as intact as possible and prevent further damage. In Afra’s case, even though she was brought into SKMC quite late with affected limbs, we quickly jumped into action with an inclusive treatment plan that prevented further deterioration of her muscles while we waited for the required genetic treatment to arrive from abroad.

This particularly helped with Afra’s breathing muscles and eliminate the need for an artificial respiratory device." The genetic treatment provided to Afra responds cures the root cause of the disease. The virus vectors targeted to the affected neurons and insert a copy of normal SMN1 gene.

Thereafter the muscle will continue to work well with improving movement and functions "I first noticed abnormal movements in Afra when she was only 3-months old and quickly consulted a pediatric physician in our home emirate. After multiple tests, Afra was diagnosed with SMA and transferred to SKMC where the medical team examined her thoroughly and implemented a robust treatment plan. I am tremendously grateful to the team at SKMC and the wider SEHA network for their diligence in treating my daughter," added Afra’s mother.

The Pediatric Neurology Service at SKMC is one of the largest and the most comprehensive services in the emirate. The pediatric neurology experts provide assessment, investigation, and management of a complete range of pediatric neurological conditions, including acute neurological disorders with common and uncommon presentation and complications.

SKMC also has specialised neuro-clinics such as BOTOX clinics, Ketogenic Diet clinic, Spina Bifida, Complex epilepsy, and neuromuscular clinic.

 

© Copyright Emirates News Agency (WAM) 2021.